Author's response to reviews Title:Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: A systematic review and network meta-analysis Authors:
نویسندگان
چکیده
Andrea C Tricco ([email protected]) Charlene Soobiah ([email protected]) Erik Blondal ([email protected]) Areti A Veroniki ([email protected]) Paul A Khan ([email protected]) Afshin Vafaei ([email protected]) John Ivory ([email protected]) Lisa Strifler ([email protected]) Huda Ashoor ([email protected]) Heather MacDonald ([email protected]) Emily Reynen ([email protected]) Reid Robson ([email protected]) Joanne Ho ([email protected]) Carmen Ng ([email protected]) Jesmin Antony ([email protected]) Kelly Mrklas ([email protected]) Brian Hutton ([email protected]) Brenda R Hemmelgarn ([email protected]) David Moher ([email protected]) Sharon E Straus ([email protected])
منابع مشابه
Safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery and chemotherapy: protocol for a systematic review and network meta-analysis
BACKGROUND Serotonin (5-HT3) receptor antagonists are a class of antiemetic medications often used to prevent nausea and vomiting among patients undergoing chemotherapy, radiotherapy or surgery. However, recent studies suggest that these agents might be associated with increased cardiac harm. To examine this further, we are proposing to conduct a systematic review and network meta-analysis on t...
متن کاملComparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis
BACKGROUND Serotonin (5-HT3) receptor antagonists are commonly used to decrease nausea and vomiting for surgery patients, but these agents may be harmful. We conducted a systematic review on the comparative safety of 5-HT3 receptor antagonists. METHODS Searches were done in MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify studies comparing 5-HT3 receptor ant...
متن کاملComparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis
BACKGROUND Serotonin (5-HT3) receptor antagonists are commonly used to decrease nausea and vomiting for surgery patients. We conducted a systematic review on the comparative efficacy of 5-HT3 receptor antagonists. METHODS Searches were done in MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify studies comparing 5-HT3 receptor antagonists with each other, place...
متن کاملComparative safety and effectiveness of serotonin receptor antagonists in patients undergoing chemotherapy: a systematic review and network meta-analysis
BACKGROUND Although serotonin (5-HT3) receptor antagonists are effective in reducing nausea and vomiting, they may be associated with increased cardiac risk. Our objective was to examine the comparative safety and effectiveness of 5-HT3 receptor antagonists (e.g., dolasetron, granisetron, ondansetron, palonosetron, tropisetron) alone or combined with steroids for patients undergoing chemotherap...
متن کاملEfficacy and safety of 5-hydroxytryptamine 3 receptor antagonists in irritable bowel syndrome: A systematic review and meta-analysis of randomized controlled trials
AIM We assessed the efficacy and safety of 5-hydroxytryptamine (5-HT3) receptor antagonists in adults with non-constipated irritable bowel syndrome (IBS) or diarrhea-predominant IBS (IBS-D). METHODS We searched PubMed, MEDLINE, EMBASE, and the Cochrane Controlled Trials Register for randomized controlled trials (RCTs) involving adults with non-constipated IBS or IBS-D that compared 5-HT3 rece...
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